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Product Details:
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Product Name: | S-23 | CAS: | 1010396-29-8 |
---|---|---|---|
MF: | C18H13ClF4N2O3 | MW: | 416.75400 |
Purity: | 99% | Appearance: | White Powder |
Usage: | Sarms For Muscle Gaining | Delivery Time: | Within 7 Working Days |
High Light: | raw sarm powder,sarms bodybuilding supplements |
Product Name
|
S-23 |
Alias
|
S23 |
CAS
|
1010396-29-8 |
MF
|
C18H13ClF4N2O3 |
MW
|
416.75400 |
Purity
|
99.50% |
Dosage
|
10mg to 15mg |
Grade
|
Pharmaceutical Grade |
Appearance
|
white crystalline powder |
Standard
|
USP |
Usage |
Male hormonal contraceptive, increase muscle mass, reduce fat |
Developed by GTx, S-23 is an orally active nonsteroidal SARM with a very high binding affinity to androgen receptors. This makes it stronger than other popular SARMS like Ostabolic (mk-2866) or Andarine (S-4). Therefore, the main effects of S-23 are increased muscle mass, decreased fat mass, and a decrease in the size of the prostate. Additionally, in a study done on rats a dose equivalent to 15 milligrams (mg) for a 180lb male was shown to also increase bone mineral density, as well as promote muscle mass growth and fat loss. Hence, S-23 is versatile in that it can be used for bulking and for cutting. S23 or (2S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide is a new SARM, which is developed as a possible male hormonal contraceptive. It links to the androgen receptor (AR) more intensely (with a Ki of 1.7nM) as compared to older medicines such as Andarine.
As of today, what we know is that S23 is an easy-to-dose oral SARM that can boost lean muscle mass growth while being tissue selective at the same time.
Sarms S23 is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc as a potential male hormonal contraceptive. It binds to the androgen receptor more strongly than older drugs such as andarine with a Ki of 1.7 nM, and in animal studies it showed both a good ratio of anabolic to androgenic effects, and dose-dependent suppression of spermatogenesis with spontaneous recovery after cessation of treatment.
A 2009 study performed on rats showed potential for S-23 to be used as a male contraceptive. In this study, six rats were given a dose of 0.1 mg per day for 10 weeks. As a result, both LH (Luteinizing Hormone) and FSH (Follicle-Stimulating Hormone) levels decreased. These effects were statistically significant, since four of the six rats had no sperm in the testis. What’s more, none of the rats was able to impregnate a female rat during mating trials. However, this contraceptive effect was temporary – after just 100 days from last dose the infertility was reversed, and there was a 100% pregnancy rate.
A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator 2. These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The peroxisome proliferator-activated receptor δ (PPARδ) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 µM.
The highest antagonist activity for GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742 behaved as PPAR agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations.
S-23 not only boosted muscle mass, but also reduced fat mass, as studied. SARMs have a bit of a 'soft' image in the doping world. They don't stimulate muscle growth in the way that anabolic steroids do, but many users say that they are safer. There are no studies yet that confirm this suspicion. But that S23 is not one of the safer SARMs - we'd be willing to wager a bottle of BCAAs on that.
S23 halts the production of sperm in the testes. In fact it does this so well that the researchers suspect S23 might be a good candidate for a male contraceptive. If this is the case it would probably have to be part of a cocktail that also contains an estradiol analogue, the researchers discovered. The lab animals lost their libido when they were given S23 on its own, and only recovered this when they were given estradiol benzoate together with the S23.
GW0742 is a synthetic, potent and selective PPAR-β/δ agonist. PPARs are ligand-dependent transcription factors which are involved in many physiological processes, such as inflammation and energy homeostasis. PPAR-β/δ is one of three PPARs in the nuclear hormone receptor superfamily that are collectively involved in the control of lipid homoeostasis among other functions.
GW0742 can attenuate the increase of PARP activity that caused by SAO shock. GW0742 is also able to prevent radiation-induced brain injury in C57Bl/6 wild-type (WT) and PPARδ knockout (KO) mice. Dietary GW0742 can prevent the acute increase in IL-1β mRNA and ERK phosphorylation measured at 3 h after a single 10-Gy dose of WBI as well as the increase in the number of activated hippocampal microglia 1 week after WBI.
S-23 not only boosted muscle mass, but also reduced fat mass, as studied. SARMs have a bit of a 'soft' image in the doping world. They don't stimulate muscle growth in the way that anabolic steroids do, but many users say that they are safer.
There are no studies yet that confirm this suspicion. But that S23 is not one of the safer SARMs - we'd be willing to wager a bottle of BCAAs on that. S23 halts the production of sperm in the testes. In fact it does this so well that the researchers suspect S23 might be a good candidate for a male contraceptive. If this is the case it would probably have to be part of a cocktail that also contains an estradiol analogue, the researchers discovered. The lab animals lost their libido when they were given S23 on its own, and only recovered this when they were given estradiol benzoate together with the S23.
Dosages of S-23 can vary, and they will be very dependent on what the goal is. For instance, if a user were looking for muscle building and fat loss, a dose of 15-25 mgs per day would be appropriate. On the other hand, if someone was looking to use it for the contraceptive effects, a higher dose of around 50 mgs per day would be more effective. Nonetheless, this is not recommended because there have not been studies done on humans to replicate the contraceptive effect shown in rats.
SARM |
Ostarine (MK-2866) |
Andarine (S4) |
Cardarine (GW-501516) |
Ligandrol (LGD-4033) |
Ibutamoren (MK-677) |
SR9009 |
RAD140 |
YK-11 |
Order Information:
MOQ: 10grams
Acceptable payment: Western Union, MoneyGram, Bitcoin and T/T
Packing & Shipping:
Packing: Strictly Packing
Express: EMS, HKEMS, FEDEX, DHL, UPS, TNT, ETK, EUB,Aramex, ETC
Shipping time: Within 24 hours
Our Competitive Advantages:
1. Rich experience: we specialize in this field for many years, our steroids have been exported almost over the world. Such as USA, Canada, UK, Brazil, Germany, Russia, Australia, Greece, Poland, Bulgaria, Rumania, Netherlands, Sweden, Ukraine, Latvia, Lithuania, Ireland, Austria, Iran, Turkey, Mexico, Thailand, India, Malaysia, Singapore, other Middle East countries, European countries, American countries and more Areas.
2. Great quality: High purity and Favorable price. Good quality is the first base of our success. All of our products enjoys high purity. Thus, it can make sure your demand. Welcome order the samples, MOQ just 10 grams.
3. Safe and fast delivery: Lots of different discreet safe packing methods, experience in choosing express, 4~7 days to arrive, successful rate 99%.
4. Experiential order and cooperation: Besides raw powders, we offer hormone solution and Recipes. We can teach you or discuss how to make hormone solution on the site. Any discussion and question is welcome!
FAQ
Q1: Have your Product Quality been Approved by Third Party Lab
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2. Are you a manufacturer?
A: Yes, we have our own factory and lab.
Q3: Is there any discount?
A: Yes, as for old customers and larger quantity, we always support with great discounts and surprise.
Q4:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card, we'd like to accept Western Union, MoneyGram, Bank Transfer, Bitcoin, Litecoin.
Q5: How do you treat quality complaint?
A: First of all, our QC department will do strict examination of our export products in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6: How to proceed order?
1st: Please let me know what you need-Which product/Cas No. quantity, and the destination country.
2nd: You send us the purchase order once we come to an agreement on all details.
3rd: Parcel would be delivered upon full payment received.
4th: Express Tracking No.will be provided about the parcels.
5th: You will get the parcels within 7days.
6th: After-sales service would be provided after you receive parcels.
Nootropic Raw Powders | ||
No. | Name | Cas no. |
1 | Sunifiram | CAS: 314728-85-3 |
2 | Pirespa | CAS: 53179-13-8 |
3 | Adrafinils | CAS: 63547-13-7 |
4 | Coluracetam | CAS: 135463-81-9 |
5 | Noopept | CAS: 157115-85-0 |
6 | Piracetam | CAS:7491-74-9 |
7 | Idebenone | CAS:58186-27-9 |
8 | Carphedon | CAS:77472-70-9 |
9 | Pramiracetam | CAS:68497-62-1 |
10 | Rivastigmine | CAS:123441-03-2 |
11 | Oxiracetam | CAS:62613-82-5 |
12 | Aniracetam | CAS:72432-10-1 |
13 | Donepezil | CAS:120014-06-4 |
14 | Rivastigmine tartrate | CAS:129101-54-8 |
15 | Alpha GPC | CAS:28319-77-9 |
16 | CRL-40,941(Fladrafinil) | CAS:90212-80-9 |
17 | Fasoracetam | CAS:110958-19-5 |
18 | Galantamine | CAS:1953-04-4 |
19 | 9-fluorenol | CAS:1689-64-1 |
20 | NSI-189 free base | CAS:1270138-40-3 |
21 | NSI-189 phosphate | CAS:1270138-41-4 |
22 | Phenibut | CAS:1078-21-3 |
23 | Picamilon | CAS:62936-56-5 |
24 | PRL-8-53 | CAS:51352-87-5 |
25 | Tianeptine sodium | CAS:30123-17-2 |
26 | Vinpocetine | CAS:42971-09-5 |
27 | Vincamine | CAS:1617-90-9 |
28 | Theacrine | CAS:2309-49-1 |
29 | Unifiram | CAS: 272786-64-8 |
30 | CDP Citicoline | CAS:987-78-0 |
31 | Huperzine A | CAS:102518-79-6 |
32 | brivaracetam | CAS:357336-20-0 |
33 | Etiracetam | CAS:33996-58-6 |
34 | Raubasine | CAS:483-04-5 |
35 | Entacapone | CAS:130929-57-6 |
Name | Purity |
Methylamine | 40% water solution |
Methylamine hydrochloride | NLT 99% |
Benzeneacetonitrile (benzyl cyanide) | NLT 99% |
Propiophenone | NLT 99.5% |
Hydrogen bromide | 48% water solution |
(-)-Dibenzoyl-L-tartaric acid monohydrate | NLT 99% |
Potassium borohydride | NLT 97% |
Sodium borohydride | NLT 98% |
6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS No:43200-81-3) | NLT 99% |
N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE (4-ANP) CAS 99918-43-1 | NLT 99% |
Pramipexole Hydrochloride | NLT 99% |
Albuterol sulfate | NLT 99% |
Dextromethorphan hydrobromide DXM | NLT 99% |
Dimethocaine | NLT 99% |
Dermorphin | 10mg/vial |
Sunifiram DM-235 | NLT 99% |
Adrafinil | NLT 99% |
Armodafinil | NLT 99% |
PHENIBUT | NLT 99% |
Suvorexant (MK-4305) | NLT 99% |
Hetlioz (tasimelteon) | NLT 99% |
Amitriptyline hydrochloride | NLT 99% |
Mirtazapine | NLT 99% |
Trazodone hydrochloride | NLT 99% |
Venlafaxine hydrochloride | NLT 99% |
Bupropion hydrochloride | NLT 99% |
Sertraline hydrochloride | NLT 99% |
N-Methylparoxetine | NLT 99% |
Paroxetine hydrochloride | NLT 99% |
Fluoxetine hydrochloride | NLT 99% |
Citalopram hydrobromide | NLT 99% |
Vortioxetine hydrobromide | NLT 99% |
Vortioxetine | NLT 99% |
Tianeptine | NLT 99% |
5-Hydroxytryptophan 5-HTP | NLT 98% |
gamma-butyrolactone (GBL) | NLT 99.5% |
5a-Hydroxy Laxogenin | NLT 98% |
Testosterone Acetate | Trenbolone Acetate | MGF |
Testosterone Cypionate | Trenbolone Enanthate | PEG MGF |
Testosterone Decanoate | Boldenone Acetate | CJC-1295 |
Testosterone Enanthate | Boldenone undecylenate | CJC-1295 DAC |
Testosterone Isocaproate | Boldenone Cypionate | PT-141 |
Testosterone Phenylpropionate | Boldenone Propionate | Melanotan-1 |
Testosterone Propionate | Nandrolone Decanoate | Melanotan-2 |
Testosterone Undecanoate | Nandrolone phenylpropionate | GHRP-2 |
Mesterone | Nandrolone undecylate | GHRP-6 |
Testosterone Sustanon 250 | Nandrolone cypionate | Ipamorelin |
Clostebol Acetate | Nandrolone propionate | Hexarelin |
Methylandrostanolone | Methyltrienolone | Sermorelin |
Methenolone Enanthate | Drostanolone Propionate | Oxytocin |
Methenolone Acetate | Drostanolone Enanthate | TB500 |
Anadrol | Stanolone | Fragment 176-191 |
Anavar | Tadalafil | Triptorelin |
Winstrol | Vardenafil | Tesamorelin |
Clomifene citrate | Dianabol | Gonadorelin |
Toremifene citrate | Tamoxifen Citrate | DSIP |
Finasteride | hydrochloride | Selank |
Benzocaine | Liothyronine sodium T3 | L-Carnitine |
Contact Person: Sales Manager