Letrozole is an anti-estrogen of the Aromatase Inhibitor family and is one of the most potent and powerfully effective of all AI's.It was first developed in an effort to combat breast cancer in post-menopausal women.Letrozole is an oral aromatase inhibitor which is a non-steroidal drug. Letrozole treats hormonally responsive breast cancer after the surgery in females past menopause. It belongs to the class of drugs known as Aromatase inhibitors and Hormones antineoplastics.It acts by decreasing the quantity of estrogen synthesized in the body.And it is one of the most commonly used anti-estrogens among steroid users during steroid use to combat possible estrogenic related side effects. It is so effective as an anti-estrogen in this regard many anabolic steroids have effectively reversed gynecomastia symptoms with Letrozole.
Letrozole (Femara) and Arimidex are the two most popular aromatase inhibitors of the 3 major AIs, with Letrozole being the second most popular.
Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor.In fact,it would prove to be virtually identical to the already popular AI in Arimidex .Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.
Letrozole has demonstrated some very incredible efficiency in the reduction of Estrogen. In comparison with the Arimidex, Letrozole has been found to be 10 – 20 times the strength of Arimidex, and although Letrozole doses are equally as effective as Aromasin, it operates through a different pathway in order to be highly effective in its own right.
For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body.
Dosage for Anabolic Steroid Use:
The general range of Letrozole doses are approximately 1.25mg – 2.5mg daily. There does exist a very large margin for adjustment and user preference when it comes to Letrozole dosages, as each individual should slowly adjust their dose depending on how they feel the body is responding. This is especially so for Letrozole, which is the most powerful and potent AI of the three. Even 1.25mg daily is too much for many anabolic steroid users, and often times the recommended dose is actually 1.25mg every other day, and often can be even less frequent especially considering the half-life of Letrozole is that of 2 – 4 days. These Letrozole doses can easily be adjusted if the user feels it is not working well enough, or if it is reducing Estrogen levels too much.
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