Growth Hormone Peptides Exenatide Acetate Lyophilized Powder CAS 141732-76-5

Basic info:

Product name: Exendin-4
Alias: Exenatide Acetate
CAS No.: 141758-74-9
EINECS: 204-035-4
Storage: Shading, confined preservation
Place of Origin: SHANGHAI, China
Molecular Formula: C184H282N50O60 S
Molecular Weight: 4186.66
Purity :99%min
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content(Karl Fischer): ≤ 10.0%
Acetate Content(HPIC): ≤ 12.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Minimum order quantity: 2mg/vial
Supply Ability: Mass stock
Packaging Details: 2mg/5mg/10mg per vial
Delivery time: 4-6 working days
Usage: Exenatide Acetate can be used to facilitate glucose control.
 

Description:

A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.

Application:

Exenatide is believed to facilitate glucose control in at least five ways:

1. Exenatide augments pancreas response and more appropriate amount of insulin that helps lower the rise in blood sugar from eating.
2. Exenatide also suppresses pancreatic release of glucagon, which prevents hyperglycemia (high blood sugar levels).
3. Exenatide helps slow down gastric emptying and thus decreases the rate at which meal-derived glucose appears in the bloodstream.
4. Exenatide has a subtle yet prolonged effect to reduce appetite, promote satiety via hypothalamic receptors.
5. Exenatide reduces liver fat content. Fat accumulation in the liver or nonalcoholic fatty liver disease (NAFLD) is strongly related with several metabolic disorders.

Packaging & Delivery:
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4. Experiential order and cooperation: Besides raw powders, we offer hormone solution and Recipes. We can teach you or discuss how to make hormone solution on the site. Any discussion and question is welcome!
Packaging & Service:
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3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
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