Safe Prohormones Muscle Building Steroids Powders Androstenedione CAS NO.63-05-8

High Purity Prohormone Steroids Powders Androstenedione CAS NO.63-05-8

Androstenedione Quick Detail

		Androstenedione, Androstendione, bASD, ADION, Andro, 4AD
		CAS: 63-05-8	EINECS: 200-554-5
		MF: C19H26O2	MW: 286.41
		Assay: 99%	Packing: 1kg/ foil bag
Grade	Pharmaceutical Grade USP28
Storage	Shading, confined preservation
Synonyms	4-AD; 4-Androstene-3,17-dione; 4-androstenedione

Androstenedione Description

4-Androstenedione is the common precursor of male and female sex hormones. Some 4-Androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.

4-Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.

The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal ovary.

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