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BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum

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BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum

BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum
BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum

Large Image :  BPC-157 CAS 137525-51-0 Human Growth Polypeptide Hormones Supplements Peptide Drum Get Best Price

Product Details:
Place of Origin: China
Brand Name: DW
Certification: GMP , ISO 9001:2008
Model Number: BPC-157
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Packaging Details: Discreet packaging
Delivery Time: Within 24 hours of receipt of payment
Payment Terms: Western Union, MoneyGram,Bitcoin, T/T
Supply Ability: 1000kg/month
Detailed Product Description
Name: BPC-157 CAS: 137525-51-0
Usage: Muscle Gaining Appearance: White Lyophilized Powder
Specification: 2mg / Vial Whatsapp: +86 13545819969
High Light:

muscle growth peptides

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muscle building peptides

Product details:

 

Product name BPC-157
Specification 2mg/vial
Appearance Lyophilized White Powder
CAS NO. 137525-51-0
Synonyms Pentadecapeptide,Bpc 15, Bpc-157, Booly protection compound 15
Molecular Weight 1419.53552
Molecular Formula C62H98N16O22

Sequence
Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Method of Analysis HPLC
Storage

Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°CBPC 157 is stable at room temperature for 90 days, It should be stored in a freezer for any extended period of time.

 

Reports »Certificate of Analysis
»HPLC Report
»Mass Spectrum

Terms
The products we offer are intended for laboratory research use only. Please familiarize yourself with our Terms and conditions prior to ordering.

 

Description:

 

BPC 157 (Body Protection Compound-157) is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice. Experiments have shown that BPC 157 enhances the healing of wounds, including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon. The study used two group of tendon explants of which one group was cultured in a BPC 157 - containing medium while the other group was cultured in a medium lacking BPC 157.


Additionally, FITC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in fibroblasts. Likewise, Western blot analysis was able to detect the production and activation of paxillin and FAK proteins. The western blot analysis also showed that BPC 157 increases the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts produced.


Stable gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, M.W. 1419) may be the new drug stable in human gastric juice, effective both in the upper and lower GI tract, and free of side effects. BPC 157, in addition to an antiulcer effect efficient in therapy of inflammatory bowel disease (IBD) (PL 14736) so far only tested in clinical phase II, has a very safe profile, and exhibited a particular wound healing effect. It also has shown to interact with the NO-saystem, providing endothelium protection and angiogenic effect, even in severely impaired conditions (i.e., it stimulated expression of early growth response 1 gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1- A binding protein-2)), important to counteract severe complications of advanced and poorly controlled IBD. Hopefully, the lessons from animal studies, particularly advanced intestinal anastomosis healing, reversed short bowel syndrome and fistula healing indicate BPC 157s high significance in further IBD therapy. Also, this supportive evidence (i.e., no toxic effect, limit test negative, LD1 not achieved, no side effect in trials) may counteract the problems commonly exercised in the use of peptidergic agents, particularly those used on a long-term basis.

 

Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic agent, safe in inflammatory bowel disease clinical trials (GEPPPGKPADDAGLV, M.W. 1419, PL 14736) and wound healing, stable in human gastric juice and has no reported toxicity. We focused on BPC 157 as a therapy in peridontitis, esophagus, stomach, duodenum, intestine, liver and pancreas lesions. Particularly, it has a prominent effect on alcohol-lesions (i.e., acute, chronic) and NSAIDs-lesions (interestingly, BPC 157 both prevents and reverses adjuvant arthritis). In rat esophagitis and failed function of both lower esophageal sphincter (LES) and pyloric sphincters (PS), BPC 157 increased pressure in both sphincters till normal and reduced esophagitis.
However, in healthy rats, it may decrease (PS) or increase (LES) the pressure in sphincters. It has strong angiogenic potential, it acts protectively on endothelium, prevents and reverses thrombus formation after abdominal aorta anastomosis, affects many central disturbances (i.e., dopamine and 5-HT system), the NO-system (either L-arginine and L-NAME effects), endothelin, acts as a free radical scavenger (counteracting CCl4-, paracetamol-, diclofenac-injuries) and exhibits neuroprotective properties.

 

Applications:

 

1). BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models.
2). BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease.
3). BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect.
BPC 157 significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle.

 

 

BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models,it may become an important therapeutic tool for the treatment of inflammatory bowel disease.BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect.And it significantly facilitates the healing of bone fracture in rats,exhibits an osteogenic effect significantly improving the healing of segmental bone defect.BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle,significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay.

 

BPC 157 successfully heals the intestinal anastomosis, gastrocutaneous, duodenocutaneous and colocutaneous fistulas in rats, as well as interacting with the NO system. Interestingly, the fistula closure was achieved even when the BPC 157 therapy was postponed for one month. In short-bowel syndrome escalating throughout 4 weeks the constant weight gain above preoperative values started immediately with BPC 157 therapy, peroral and parenteral, and the villus height, crypt depth and muscle thickness additionally increased. Thus, BPC 157 may improve gastrointestinal tract therapy.


BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker, L-NAME (prothrombotic) and the NOS-substrate L-arginine (antithrombotic), were little investigated. Objective. To investigate the effect of L-NAME and L-arginine on hemostatic parameters, and to reveal the effects of BPC 157 on the L-NAME- and L-arginine-induced hemostatic actions under different pathological condition: tail amputation without or with anticoagulants, heparin or warfarin.


BPC 157 was proven to speed-heal tears in quadriceps muscles, as it also promoted faster healing of Achilles tendons, damaged muscle tissue and crushed muscle tissue. It also helped with recovery from torn muscles.


This peptide is also believed to decrease pain in damaged areas. Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide, once it is approved for usage in human subjects.

 

 

 

Our Compamy Advantages:

 

1, High quality with competitive price:
1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.


2, Fast and safe delivery
1) Parcel can be sent out within 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.

3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

Email:doublewin-wendy@nandrolonesteroid.com

Whatsapp:+86 13545819969

Skype:Wendy.Doublewin

Web site:http://www.nandrolonesteroid.com/

 

 

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